Chronic renal failure disease – symptoms, causes, diagnosis & stem cell therapy

Chronic Renal Failure, also called chronic kidney disease (CKD), is slow kidney damage over months or years. High blood pressure and diabetes are the main causes. Kidney infections, things blocking the urinary tract, and long-term medication use can also lead to CKD. Symptoms include issues with urination, puffy eyes, swelling in hands and feet, high blood pressure, tiredness, not feeling hungry, and breath shortness. Testing the blood and urine helps check how kidneys are working. Stem cell therapy is a new hope for CKD, showing it might reverse kidney damage and boost kidney function.

Key Takeaways:

• Chronic kidney disease (CKD) means kidneys slowly stop working.
• High blood pressure and diabetes are the main causes. But, kidney infections and blockages can also be reasons.
• Signs of CKD are odd urination, puffy eyes, and swelling. Plus, high blood pressure, tiredness, not being hungry, and breath problems.
• To diagnose CKD, doctors take blood and urine to test kidney function.
• Stem cell therapy is a new hope for CKD. It could help fix kidney damage and make kidneys work better.

Chronic renal failure is a severe health issue needing careful care and treatment. Thanks to progress in stem cell therapy, there’s hope that CKD patients could see their kidney function improve. Always talk to a doctor to learn about the best treatment options for chronic renal failure.

Types of Renal Diseases

Chronic renal failure comes from many renal diseases. Knowing these diseases is key to dealing with chronic kidney disease (CKD).

1. Glomerulonephritis: It is the inflammation and harm of the glomeruli. Glomeruli are the tiny blood vessels in the kidneys. Infections, autoimmune diseases, and viral illnesses can cause this.

2. Polycystic Kidney Disease (PKD): PKD comes from a genetic disorder. It causes fluid-filled cysts in the kidneys. Over time, these cysts can harm the kidneys and cause them to fail.

3. IgA Nephropathy: In IgA nephropathy, a specific antibody, immunoglobulin A, builds up in the kidneys. This leads to inflammation and damage in the kidneys.

4. Renal Artery Stenosis: Renal artery stenosis is the narrowing of the arteries that carry blood to the kidneys. This causes reduced blood flow. It can lead to kidney dysfunction.

5. Renal Cell Carcinoma: Known as kidney cancer, renal cell carcinoma starts in the kidney cells. It affects how the kidneys work. In advanced stages, it can cause kidney failure.

6. Reflux Nephropathy: Reflux nephropathy happens when urine flows back into the kidneys from the bladder. This can cause kidney infections and damage over time.

7. Acute Renal Failure: Acute renal failure is the sudden loss of kidney function. Severe infections, certain medications, or kidney injuries can cause it.

Every renal disease has unique causes, symptoms, and treatments. Detecting and managing these issues is crucial to stop or slow down chronic renal failure.

Comparison of Renal Disease Types

Five Stages of Kidney Disease

Chronic kidney disease (CKD) gets worse over time. It has five stages, based on how well the kidneys filter blood. These stages show how bad the kidney damage is and help with treatment choices.

Stage 1 of kidney disease is the first level. It has little kidney damage and normal blood filtering. People here might not show any symptoms.

Stage 2 of kidney disease comes next. It shows mild kidney damage and a slight drop in filtering ability. Symptoms can include feeling tired or changes in how much you pee.

Stage 3 has two parts, 3A and 3B. In stage 3A, kidney function is moderately reduced, with an eGFR between 45-59 mL/min/1.73m². In stage 3B, the reduction is steeper, with an eGFR between 30-44 mL/min/1.73m². Symptoms like swelling, tiredness, anemia, and high blood pressure may show up.

In Stage 4, the damage is severe. The eGFR falls between 15-29 mL/min/1.73m². Signs can be fatigue, nausea, not feeling hungry, and trouble concentrating. At this point, treatments like dialysis or a kidney transplant are important choices.

Stage 5, the last one, is when the kidneys stop working fully. The eGFR is under 15 mL/min/1.73m². At this stage, dialysis or a kidney transplant is vital to stay alive.

Knowing the five stages allows doctors to check how badly CKD has progressed. It helps them plan the right treatments. Catching CKD early and treating it can slow damage and help patients live better.

Conclusion

Stem cell therapy shines as a beacon of hope for those battling chronic kidney disease. It has shown the power to heal by reversing damage and boosting kidney function. This leads to less need for dialysis or transplants. By introducing healthy cells where there is damage, the therapy works towards full kidney restoration.

One major plus of this therapy is how well it works. Patients often see their kidney function get better after undergoing treatment. It is also a very safe method, with little risk of any negative effects. This ensures that patients are in the best hands.

Let’s not forget about its price tag. Getting this treatment in India is much cheaper than in some other places. So, it’s a more affordable choice for those in need of cutting-edge care.

In the end, stem cell therapy for chronic kidney disease is a game-changer. It offers hope for a future where kidneys can heal. Thanks to its success and cost benefits, many more people may have access to this life-changing option soon.